Synuclein alpha Antibodies

α-synuclein is a protein of 140 amino acids and a member of the synuclein family. It may be implicated in the formation of Lewy bodies and the selective degeneration of neurons in sporadic Parkinson's disease and Lewy body dementia. This antibody is specific for α-synuclein and does not cross react with β-synuclein and will be useful for the confirmation of Parkinson's disease and Lewy body dementia and other studies for the localization and detection of α-synuclein.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Rat. Others not tested.

Epitope: Near C-terminus

Immunogen: A synthetic peptide derived from near C-terminus of human α-Synuclein

Molecular Weight: 15kDa

Positive Control: Posterior cingulated gyrus

Cellular Localization: Neuronal cytosol and presynaptic terminals

Recommended for:

Immunohistochemistry (Formalin/paraffin)

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